Biblio

Found 40 results
Filters: Keyword is Humans  [Clear All Filters]
2015
Wettstein S, Underhaug J, Perez B, Marsden BD, Yue WW, Martinez A, Blau N.  2015.  Linking genotypes database with locus-specific database and genotype-phenotype correlation in phenylketonuria.. Eur J Hum Genet. 23(3):302-9.
erný JČ, Biedermannová L, Mikulecký P, Zahradník J, Charnavets T, ebo PŠ, Schneider B.  2015.  Redesigning protein cavities as a strategy for increasing affinity in protein-protein interaction: interferon- γ receptor 1 as a model.. Biomed Res Int. 2015:716945.
2014
McKeone R, Wikstrom M, Kiel C, Rakoczy EP.  2014.  Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa.. Mol Vis. 20:183-99.
Xi Y, Wu X, Gao L, Shao Y, Peng H, Chen H, Chen H, Hu X, Yue J.  2014.  Improving the anti-toxin abilities of the CMG2-Fc fusion protein with the aid of computational design.. PLoS One. 9(8):e104674.
Kiel C, Serrano L.  2014.  Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations.. Mol Syst Biol. 10:727.
2012
Kimberley FC, van der Sloot AM, Guadagnoli M, Cameron K, Schneider P, Marquart AJ, Versloot M, Serrano L, Medema J P.  2012.  The design and characterization of receptor-selective APRIL variants.. J Biol Chem. 287(44):37434-46.
Simões-Correia J, Figueiredo J, Lopes R, Stricher F, Oliveira C, Serrano L, Seruca R.  2012.  E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancer.. PLoS One. 7(3):e33783.
De Baets G, Van Durme J, Reumers J, Maurer-Stroh S, Vanhee P, Dopazo J, Schymkowitz J, Rousseau F.  2012.  SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants.. Nucleic Acids Res. 40(Database issue):D935-9.
2011
Verschueren E, Vanhee P, van der Sloot AM, Serrano L, Rousseau F, Schymkowitz J.  2011.  Protein design with fragment databases.. Curr Opin Struct Biol. 21(4):452-9.
2007
Kiel C, Foglierini M, Kuemmerer N, Beltrao P, Serrano L.  2007.  A genome-wide Ras-effector interaction network.. J Mol Biol. 370(5):1020-32.
Pey AL, Stricher F, Serrano L, Martinez A.  2007.  Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases.. Am J Hum Genet. 81(5):1006-24.
Szczepek M, Brondani V, Büchel J, Serrano L, Segal DJ, Cathomen T.  2007.  Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases.. Nat Biotechnol. 25(7):786-93.
2006
van der Sloot AM, Tur V, Szegezdi E, Mullally MM, Cool RH, Samali A, Serrano L, Quax WJ.  2006.  Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor.. Proc Natl Acad Sci U S A. 103(23):8634-9.
2005
Wohlgemuth S, Kiel C, Krämer A, Serrano L, Wittinghofer F, Herrmann C.  2005.  Recognizing and defining true Ras binding domains I: biochemical analysis.. J Mol Biol. 348(3):741-58.
Kiel C, Wohlgemuth S, Rousseau F, Schymkowitz J, Ferkinghoff-Borg J, Wittinghofer F, Serrano L.  2005.  Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations.. J Mol Biol. 348(3):759-75.