Biblio

Found 152 results
2012
De Baets G, Van Durme J, Reumers J, Maurer-Stroh S, Vanhee P, Dopazo J, Schymkowitz J, Rousseau F.  2012.  SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants.. Nucleic Acids Res. 40(Database issue):D935-9.
2011
Vanhee P, Verschueren E, Baeten L, Stricher F, Serrano L, Rousseau F, Schymkowitz J.  2011.  BriX: a database of protein building blocks for structural analysis, modeling and design.. Nucleic Acids Res. 39(Database issue):D435-42.
Van Durme J, Delgado J, Stricher F, Serrano L, Schymkowitz J, Rousseau F.  2011.  A graphical interface for the FoldX forcefield.. Bioinformatics. 27(12):1711-2.
Verschueren E, Vanhee P, van der Sloot AM, Serrano L, Rousseau F, Schymkowitz J.  2011.  Protein design with fragment databases.. Curr Opin Struct Biol. 21(4):452-9.
2008
Tokuriki N, Stricher F, Serrano L, Tawfik DS.  2008.  How protein stability and new functions trade off.. PLoS Comput Biol. 4(2):e1000002.
Baeten L, Reumers J, Tur V, Stricher F, Lenaerts T, Serrano L, Rousseau F, Schymkowitz J.  2008.  Reconstruction of protein backbones from the BriX collection of canonical protein fragments.. PLoS Comput Biol. 4(5):e1000083.
2007
Kölsch V, Seher T, Fernandez-Ballester GJ, Serrano L, Leptin M.  2007.  Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2.. Science. 315(5810):384-6.
Kiel C, Foglierini M, Kuemmerer N, Beltrao P, Serrano L.  2007.  A genome-wide Ras-effector interaction network.. J Mol Biol. 370(5):1020-32.
Pey AL, Stricher F, Serrano L, Martinez A.  2007.  Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases.. Am J Hum Genet. 81(5):1006-24.
Kiel C, Serrano L.  2007.  Prediction of Ras-effector interactions using position energy matrices.. Bioinformatics. 23(17):2226-30.
Tokuriki N, Stricher F, Schymkowitz J, Serrano L, Tawfik DS.  2007.  The stability effects of protein mutations appear to be universally distributed.. J Mol Biol. 369(5):1318-32.
Szczepek M, Brondani V, Büchel J, Serrano L, Segal DJ, Cathomen T.  2007.  Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases.. Nat Biotechnol. 25(7):786-93.
2006
Kempkens O, Médina E, Fernandez-Ballester G, Ozüyaman S, Le Bivic A, Serrano L, Knust E.  2006.  Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6.. Eur J Cell Biol. 85(8):753-67.
van der Sloot AM, Tur V, Szegezdi E, Mullally MM, Cool RH, Samali A, Serrano L, Quax WJ.  2006.  Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor.. Proc Natl Acad Sci U S A. 103(23):8634-9.
Arnould S, Chames P, Perez C, Lacroix E, Duclert A, Epinat J-C, Stricher F, Petit A-S, Patin A, Guillier S et al..  2006.  Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets.. J Mol Biol. 355(3):443-58.
Musi V, Birdsall B, Fernandez-Ballester G, Guerrini R, Salvatori S, Serrano L, Pastore A.  2006.  New approaches to high-throughput structure characterization of SH3 complexes: the example of Myosin-3 and Myosin-5 SH3 domains from S. cerevisiae.. Protein Sci. 15(4):795-807.
Kiel C, Serrano L.  2006.  The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes.. J Mol Biol. 355(4):821-44.
2005
Schymkowitz J, Borg J, Stricher F, Nys R, Rousseau F, Serrano L.  2005.  The FoldX web server: an online force field.. Nucleic Acids Res. 33(Web Server issue):W382-8.
Schymkowitz JWH, Rousseau F, Martins IC, Ferkinghoff-Borg J, Stricher F, Serrano L.  2005.  Prediction of water and metal binding sites and their affinities by using the Fold-X force field.. Proc Natl Acad Sci U S A. 102(29):10147-52.
Wohlgemuth S, Kiel C, Krämer A, Serrano L, Wittinghofer F, Herrmann C.  2005.  Recognizing and defining true Ras binding domains I: biochemical analysis.. J Mol Biol. 348(3):741-58.
Kiel C, Wohlgemuth S, Rousseau F, Schymkowitz J, Ferkinghoff-Borg J, Wittinghofer F, Serrano L.  2005.  Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations.. J Mol Biol. 348(3):759-75.
2004
Kiel C, Serrano L, Herrmann C.  2004.  A detailed thermodynamic analysis of ras/effector complex interfaces.. J Mol Biol. 340(5):1039-58.
2002
Guerois R, Nielsen J E, Serrano L.  2002.  Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations.. J Mol Biol. 320(2):369-87.
1999
Petukhov M, Cregut D, Soares CM, Serrano L.  1999.  Local water bridges and protein conformational stability.. Protein Sci. 8(10):1982-9.
1998
Vijayakumar M, Wong KY, Schreiber G, Fersht AR, Szabo A, Zhou HX.  1998.  Electrostatic enhancement of diffusion-controlled protein-protein association: comparison of theory and experiment on barnase and barstar.. J Mol Biol. 278(5):1015-24.